While a myriad of health education and prevention programs exist in the community and on HBCU college campuses, most women are unaware of these resources and, most importantly, the availability and effectiveness of pre-exposure prophylaxis (PrEP), despite being at greater risk of HIV. Black Women and HIV: Empowerment through Engagement, Education, and Enrichment (“Empower”) is an HBCU led, collaborative, multi-year initiative committed to advancing HIV prevention and sexual health among Black women by implementing culturally responsive education and community engagement.