Expanded screening for hepatitis C virus (HCV) infection aims to improve awareness of diagnosis, yet treatment uptake remains suboptimal due to structural, social, and individual-level barriers. People who use drugs face further challenges in accessing HCV treatment due to fragmented care, stigma, and limited support. Strategies to overcome these challenges are needed to improve health equity and achieve HCV elimination. We developed a quality improvement pilot project to integrate expedited DAA initiation, defined as prescribing of DAA during hospital admission.