The Department of Health and Human Services developed a National Strategic Plan to eliminate hepatitis C (HCV) as a public health threat by 2030. However, many barriers to accessing care remain. Pharmacists have increasingly played a role in the treatment of HCV and can support patients and care teams with navigating barriers at multiple steps along the care cascade. The Collaborative Drug Therapy Management (CDTM) model offers a strategy to leverage expertise of embedded pharmacists to improve HCV treatment access and outcomes.