Hepatitis C (HCV) remains a curable yet under-treated infection, especially in populations impacted by structural inequities such as homelessness, substance use, incarceration, and lack of insurance. Although curative treatments are now simplified, many primary care providers still feel undertrained, unsupported, or unsure how to incorporate HCV treatment into their clinical workflows. This “Hep C Crash Course” is designed to bridge that gap and empower primary care and other community-based providers to confidently screen, diagnose, and treat HCV within outpatient settings using a simplified and scalable model.

This session provides a five-step roadmap for integrating HCV care into primary care practice. Attendees will learn how to conduct reflex-based screening, stage fibrosis using labs or portable tools, select treatment regimens aligned with AASLD-IDSA guidelines, navigate medication access barriers, and monitor patients through to sustained virologic response (SVR).

The session also addresses the syndemic of HCV, HIV, and opioid use disorder, highlighting strategies to engage patients through trauma-informed care, harm reduction, and community partnerships. Special attention will be given to populations often excluded from specialty care, including people who use drugs, those experiencing homelessness, and individuals reentering the community from incarceration.

Participants will leave with clinical decision tools, sample workflows, and resources to begin or expand HCV treatment in their own clinics and ultimately improving access, outcomes, and equity in care.